Book Description
Inside Optical Coherence Tomography Angiography of the Eye Drs. David Huang, Bruno Lumbroso, Yali Jia, and Nadia Waheed include detailed information on clinical applications and fundamental principles needed to understand and use this new technology. This includes information on high-speed OCT systems, algorithms to extract flow contrast, the appearance of the normal eye, the findings in myriad diseases, and tips on how to deal with artifact and pitfalls.
The 3-dimensional nature of OCT angiography provides visualization that was not possible before with either FA or ICG and readers will come to appreciate how this enables the visualization of previously difficult to image vascular beds such as the 4 retinal vascular plexuses (radial peripapillary, superficial, intermediate, and deep), the choriocapillaris, and the deeper choroidal vessels.
Given its noninvasive nature and ease of use, OCT angiography imaging is rapidly taking an important place in everyday ophthalmology and may soon replace fluorescein angiography in everyday practice.
Optical Coherence Tomography Angiography of the Eye is designed to be the definitive text on this cutting-edge technology for the retina specialist and comprehensive ophthalmologist.
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Contents
Dedication
Acknowledgments
About the Editors
Contributing Authors
Introduction
Part I: Principles and Methods
Chapter 1 Optical Coherence Tomography Systems for Angiography
Gangjun Liu, PhD; Alex D. Pechauer, BS; David Huang, MD, PhD; and James G. Fujimoto, PhD
Chapter 2 Optical Coherence Tomography Angiography Algorithms
Yali Jia, PhD; Simon S. Gao, PhD; and David Huang, MD, PhD
Chapter 3 Cross-Sectional and En Face Visualization of Posterior Eye Circulations
Yali Jia, PhD; Bruno Lumbroso, MD; Simon S. Gao, PhD; David Huang, MD, PhD;
and David J. Wilson, MD
Chapter 4 Cross-Sectional and En Face Visualization of Normal Anterior Eye Circulations
Yan Li, PhD; Yali Jia, PhD; David Huang, MD, PhD; and Alison H. Skalet, MD, PhD
Chapter 5 Artifacts in Optical Coherence Tomography Angiography
Simon S. Gao, PhD; Yali Jia, PhD; and David Huang, MD, PhD
Chapter 6 Quantification
Yali Jia, PhD; Acner Camino, PhD; Miao Zhang, PhD; Simon S. Gao, PhD;
and David Huang, MD, PhD
Chapter 7 Optical Coherence Tomography Angiography: Terminology
David Huang, MD, PhD and Simon S. Gao, PhD
Chapter 8 Optical Coherence Tomography Angiography on the Optovue AngioVue With
Split-Spectrum Amplitude-Decorrelation Angiography and DualTrac Motion Correction
Tony Ko, PhD and Jay Wei, MS
Chapter 9 Optical Coherence Tomography Angiography: Optical Microangiography
Ruikang K. Wang, PhD; Qinqin Zhang, PhD; Giovanni Gregori, PhD;
and Philip J. Rosenfeld, MD, PhD
Chapter 10 Optical Coherence Tomography Angiography Imaging With Topcon’s One-Micrometer
Wavelength Swept Source Optical Coherence Tomography
Charles Reisman, MS; Atsushi Kubota, MS; Masahiro Akiba, PhD;
Catharine Chisholm, PhD; and Michael J. Sinai, PhD
Chapter 11 Spectral Domain Optical Coherence Tomography
Angiography Using NIDEK RS-3000 Advance
Mayss Al-Sheikh, MD and SriniVas R. Sadda, MD
Part II: Retinal Diseases
Chapter 12 Exudative Neovascular Age-Related Macular Degeneration
Type 1, 2, and Mixed Choroidal Neovascularization
Bruno Lumbroso, MD; Steven T. Bailey, MD; Yali Jia, PhD; Marco Rispoli, MD;
and Maria Cristina Savastano, MD
Chapter 13 Short- and Long-Term Response of Choroidal
Neovascularization to Anti-Angiogenic Treatment
Bruno Lumbroso, MD; Steven T. Bailey, MD; Yali Jia, PhD; Marco Rispoli, MD;
and Maria Cristina Savastano, MD
Chapter 14 Nonexudative Neovascular Age-Related Macular Degeneration
Steven T. Bailey, MD; Ching J. Chen, MD; and Yali Jia, PhD
Chapter 15 Type 3 Neovascularization—Retinal Angiomatous Proliferation
Anna C.S. Tan, MBBS, FRCSED; Kunal K. Dansingani, MA, FRCOphth;
and K. Bailey Freund, MD
Chapter 16 Non-Neovascular Age-Related Macular Degeneration
Ricardo N. Louzada, MD; Nadia K. Waheed, MD, MPH; Jay S. Duker, MD;
and Mark Lane, MBBS Honors
Chapter 17 Polypoidal Choroidal Vasculopathy
Min Wang, MD, PhD; Simon S. Gao, PhD; and Yali Jia, PhD
Chapter 18 Optical Coherence Tomography Angiography of Macular Telangiectasia Type 2
Ching J. Chen, MD; Brian Tieu, MD, PhD; and Matthew Olson, CRA
Chapter 19 Central Serous Chorioretinopathy
Eduardo A. Novais, MD; Mark Lane, MBBS Honors;
Nadia K. Waheed, MD, MPH; and Jay S. Duker, MD
Chapter 20 Choroidal Neovascularization of Other Causes
Brian K. Do, MD; Richard I. Kaplan, MD; Patricia Garcia, MD;
Andre Romano, MD; and Richard Rosen, MD;
Chapter 21 Nonproliferative Diabetic Retinopathy
Thomas Hwang, MD; Yali Jia, PhD; Miao Zhang, PhD; and David J. Wilson, MD
Chapter 22 Proliferative Diabetic Retinopathy
Emily D. Cole, BS; Nadia K. Waheed, MD, MPH; and Jay S. Duker, MD
Chapter 23 Retinal Venous Occlusion
Marco Rispoli, MD and Bruno Lumbroso, MD
Chapter 24 Retinal Arterial Occlusion
Xiaogang Wang, MD, PhD; Jing Dong, MS; and Yading Jia, BS
Chapter 25 Inherited Retinal Degenerations
Rachel Patel, MD; Simon S. Gao, PhD; Paul Yang, MD, PhD; Richard G. Weleber, MD;
David J. Wilson, MD; and Mark Pennesi, MD, PhD
Chapter 26 Pathological Myopia
Leonardo Mastropasqua, MD and Luca Di Antonio, MD, PhD
Chapter 27 Flow Characteristics in Retinal Vasculitis Using
Optical Coherence Tomography Angiography
Phoebe Lin, MD, PhD; Miao Zhang, PhD; and Liang Liu, MD
Chapter 28 White Dot Syndromes
Philipp K. Roberts, MD; Lee Jampol, MD; and Amani A. Fawzi, MD
Chapter 29 Optical Coherence Tomography Angiography in
Choroiditis, Retinitis, and Vasculitis
Andre Romano, MD; Rubens Belfort Jr, MD, PhD; and Daniela Ferrara, MD, PhD
Chapter 30 Melanocytic Tumors
Alison H. Skalet, MD, PhD; David Huang, MD, PhD; Yali Jia, PhD; and Yan Li, PhD
Chapter 31 Radiation Maculopathy
Alexandre Matet, MD; Aude Ambresin, MD; Gilda Cennamo, MD; and Leonidas Zografos, MD
Part III: Optic Nerve Diseases
Chapter 32 Optical Coherence Tomography Angiography in Primary Open-Angle Glaucoma
David Huang, MD, PhD; Liang Liu, MD; and Michel Puech, MD, MSC
Chapter 33 Primary Angle-Closure Glaucoma
Chunhui Jiang, MD, PhD and Xinghuai Sun, MD, PhD
Chapter 34 Neurodegenerative Diseases
Albert J. Augustin, MD and Christian Dempe
Part IV: Anterior Diseases
Chapter 35 Angiography of the Cornea Using Optical Coherence Tomography
Winston Chamberlain, MD, PhD; Afshan Nanji, MD, MPH; David Huang, MD, PhD;
and Yan Li, PhD
Financial Disclosures
Index
About the Editors
Bruno Lumbroso, MD has been Director of the Department of Ophthalmology of the Rome Eye Hospital (Rome, Italy) and Professor LD of Clinical Ophthalmology at the University of Rome La Sapienza (Rome, Italy) for more than 35 years. He is now Directorof the private Centro Italiano Macula in Rome, Italy. He was a pioneer in the development of clinical applications for en face OCT and OCT angiography. He is co-founder and General Secretary of the Societa Italiana di Angiografia OCT and of the Societa Italiana di Laser in Oftalmologia. His main interests are in logical methods of retinal imaging analysis and interpretation, and in clinical applications of OCT and OCT angiography technology for retinal disorders.
Yali Jia, PhD is an Assistant Professor of Ophthalmology and Biomedical Engineering at the Oregon Health & Science University (OHSU) in Portland, Oregon. Dr. Jia earned her PhD in Biomedical Engineering from OHSU in 2010 under the guidance of Dr. Ruikang Wang. Dr. Jia completed her post-doctoral training with Dr. David Huang at Casey Eye Institute in 2013. She developed split-spectrum amplitude de-correlation angiography (SSADA), a highly efficient optical coherence tomography angiography (OCTA) algorithm that made clinical OCTA practical. Her article on SSADA, published in Optics Express in 2012, has been cited more than 430 times. Dr. Jia was awarded 3 National Institute of Health research project grants that supported the initial works that demonstrated clinical applications of OCTA in retinal diseases. She is the technical leader in Casey Reading Center. Her OCTA reading software (COOL-ART) has been used by several large clinical studies and many international collaborators. She has published 75 peer-reviewed journal articles and 25 book chapters; and co-edited 3 books. Her major contributions to the OCTA community are: efficient OCTA, quantitative OCTA, projection-resolved OCTA and motion-free OCTA.
Nadia K. Waheed, MD, MPH is Director of the Boston Image Reading Center and Associate Professor in Ophthalmology at the Tufts University School of Medicine (Boston, Massachusetts). She specializes in clinical and clinical trial applications of optical coherence tomography and optical coherence tomography angiography.